The HAMSTER ANTI MOUSE CD61:RPE Antibody from MyBioSource.com is a Hamster Monoclonal antibody to CD61, GP3A, GPIIIa, Integrin beta, Integrin beta 3, Integrin Beta3, and ITGB3. This antibody recognizes Mouse antigen. The HAMSTER ANTI MOUSE CD61:RPE Antibody has been validated for the following applications: Flow Cytometry.
Description
Hamster anti Mouse CD61 antibody, clone HM beta 3-1 recognizes the murine integrin beta 3 subunit (CD61), a 90kDa a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptor for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin. Hamster anti Mouse CD61 antibody, clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin (Yasuda et al. 1995)